★★★★☆March 3, 2016
Best hand cream on the market!
Love the silky feeling I get when I moisturize my hands with Glysomed. Helps with hands that are very dry and split cuticles. I would have given 5 stars but didn't only because it does leave a residue until fully absorbed.
ChristineVerified purchaseHelpful (3)
★★★★★March 23, 2023
Lighten my hands and healed them completely!
Before I used this stuff, the inner folds of my hand were incredibly dry. I was use a nail file/foot scrapper to smooth out my dry hands and was applying Vaseline/Neosporin. Which help for a bit, but it was only temporary because it would go back after 6 hours after using this stuff. It took me only 1 1/2 week for my hands to fully heal! In my second photo was taken on day 4 and it was working so fast! My first photo is how my hand looks now! Even would like to mention my hands had hyperpigmentation for a while too!
Shwetty999Verified purchaseHelpful (2)
★★★★★December 15, 2023
So silky
I work with soil all day and my hands can get super dry. I read the reviews and was a little skeptical, but wow! It does an awesome job with moisturizing and smells great
Claudia T.Verified purchaseHelpful (1)
★★★★★March 30, 2024
Take it from a Nurse...
Take it from a Nurse, this is the best hand lotion you will ever encounter. As someone who washes their hands multiple times a day, as well as having my hands in patient faces- taking their temperature, etc- my paws need to look good! This lotion leaves a layer of protection that provides a barrier with handwashing throughout the day. Hands feel great and look healthy!
Heidi-MakesWineDisappearVerified purchaseHelpful (1)
★★★★★April 26, 2022
Best hand cream
I'm a nurse and I wash my hands alot. This is the most moisturizing lotion. It has a silky finish and light clean smell. 2 thumbs up!
Rebecca BenedictVerified purchaseHelpful (1)
★★★★★December 6, 2016
HIGHLY RECOMMEND
I love this stuff! Due to the ingredients and probably the silicone, the lotion covers my dry hands very well! I wash my hands religiously, and this is my new go-to lotion. Other than its generous size, the smell is mild which is great, and I can usually still detect it on my skin after I wash my hands once more, which I also love.
Amazon CustomerVerified purchaseHelpful (1)
★★★★★February 18, 2019
This stuff is amazing
I have eczema that mostly affects my hands and feet. I've been getting flare after flare this winter to the point that my hands are like velcro. I was having to wear cotton gloves to do laundry or my hands would stick to the clothes. My skin was flaking off - I felt like a molting lizard. Someone else with eczema recommended this product. Now, besides having eczema, I have generally sensitive skin. I can use a product made with eczema sufferers in mind and end up having my eczema flare. So I didn't know if I'd be throwing away money with this. Well ... within 24 hours of starting to use this, my hands were healed enough that they no longer felt like velcro. Within 48 hours, my hands were almost completely healed. I'm a fan now. I'm going to try the foot cream next.
Tami & JeremyVerified purchaseHelpful (1)
★★★★★September 9, 2017
The BEST hand cream EVER!
A coworker introduced me to this product in 2004 and I've been a devotee ever since. It just takes a tiny amount and it makes my hands feel so good! It also lasts all day. I've shared it with many friends and they're now fans, too. If you have really dry hands and nothing seems to help, try this product! You won't be disappointed.
E. MooneyVerified purchaseHelpful (1)
★★★★★June 8, 2017
The best hand creme there is
The best hand creme there is. I have a very sensitive skin and skin dryness problem. My skin cracks and i get calluses on my knuckles and it turns dark and ugly. Only this hand creme solves my skin problem. I loved this hand creme. I even had my friends tried it and they all liked it. You should give this Glysomed hand creme a try and i assure you won't regret.
LARRY AMENAVerified purchaseHelpful (1)
★★★★★May 20, 2022
Great Stuff!!
This product is BETTER than described. It is nice smelling, clean, non-greasy and really absorbs into your skin. I'm buying it again.
Jan JohnsonVerified purchase
★★★★★May 16, 2024
Best lotion
Best lotion I’ve gotten in awhile. Non greasy and actually heals your hands.
JoannaVerified purchase
★★★★★April 8, 2024
Soft cream
Good for hand cream
JonalieVerified purchase
★★★★★April 14, 2023
Moisture
Very coating to the skin
lanisha smallwoodVerified purchase
★★★★★October 13, 2023
Love this product!
It makes your hands so soft!
Lisa RogersVerified purchase
★★★★★July 25, 2026
Very good with dry skin
This is the go-to lotion in our house. I make sure I have this in the full size and travel size. Very good with dry skin.
Mama TVerified purchase
★★★★★February 23, 2026
Works great for dry hands
Always luv this product
Margaret M. CatagnusVerified purchase
★★★★★December 3, 2023
La mejor
La mejor crema que he probado para mis manos.
nelyVerified purchase
★★★★★April 18, 2024
Lasts thru hand washing
This has got to be my favorite lotion. I found this about 10 years ago and it literally stops my fingers from splitting in the winter. Apply morning and night time for that extra boost of protection. Love love love this!
NoraVerified purchase
★★★★★February 1, 2025
Best handcream
This hand cream is a lifesaver! My hands were so dry my knuckles were bleeding. After a few days of applying my hands healed & are so soft!
Pam WatkinsVerified purchase
★★★★★February 3, 2024
It works!!!
Was so happy to find Glisomel on Amazon after looking for years, after buying a sample at WalMart. Every winter my hands are so sore with cracked fingers. This is the only product I have found that really works and my hands are so soft.🥰
PatVerified purchase
★★★★★January 4, 2026
Great cream
This is the best hand cream I've tried by far.
YaraVerified purchase
★★★★★November 6, 2024
really good
Great lotion for hands or feet
Amazon CustomerVerified purchase
★★★★★March 13, 2024
Amazing hand cream
One of the best hand creams you could buy
BranVerified purchase
★★★★★April 24, 2026
Soft silky hands! (And feet!)
Best lotion on the planet! I’m in healthcare and so get to wash my hands A LOT. I’ve been using this stuff for probably 20 years. So thankful they brought it out in a large tube. Best price you’ll find. It seems to even retain effectiveness after a hand wash or two, as long as it’s not super harsh soap. Try it. You’ll love it. It does have a slight perfume to it, which I like, but they do make fragrance feel also.
Christine MurphyVerified purchase
★★★★★December 20, 2023
The best
This is so different from any other hand cream. It’s rich and block moisture on my hand.just a dap of it
daisyVerified purchase
★★★★★February 7, 2024
Not greasy
Smells like glycerin soap. I like that it's not so greasy feeling and can use right after I wash my hands multiple times a day.
Dinosaur BloodVerified purchase
★★★★★February 3, 2024
The absolute best
Simply the best hand cream for dry, cracked skin, and preventing the same, hands down. Have used it for years and not about to stop.
Drew400Verified purchase
★★★★★December 8, 2023
Hand cream
Love the way it feels and smells
Gail A ByrdVerified purchase
★★★★★March 26, 2026
Quality cream that your body will love
I gave it as a gift to my mom and she loved the smell and how soft it made her skin feel. Review was great that I bought another one for my sister.
IvyVerified purchase
★★★★★October 23, 2024
Love
Makes my hands feel so soft and moisturized
tVerified purchase
★★★★★September 10, 2024
Moisture
Perfect for ur hands
WaqasVerified purchase
★★★★★November 14, 2024
Es la mejor
No he visto estas cremas en venta libre en farmacias etc, no entiendo a razón. Es la mejor, me ayudó durante mi embarazo a no tener ni una sola estría.
ALE ARRUEBAVerified purchase
★★★★★September 14, 2025
I Like It
I like it. This brand works well on my old desert soaked skin! Softens my skin.
Ron RVerified purchase
★★★★★January 30, 2024
Worlds best hand lotion
The very best hand lotion you can buy. I have tried so many and either they are super runny, or leave your hands greasy, or smell weird or simple don’t work. This is the best one hands down. I have never bought another kind since I discovered this one. Smells lovely, goes on smooth, is not greasy and works so well! Highly recommend it!
Sara DVerified purchase
★★★★☆September 14, 2025
Hand cream
Non greasy, it makes my hands feel soft and moist.
Amazon CustomerVerified purchase
★★★☆☆March 20, 2024
Moisturizes well but not for those sensitive to smell
My partner bought this for my eternally dry and cracked hands (I am an obsessive hand washer). Nice hand cream but unfortunately the smell is floral and borders on chemically to me. For those with sensitive noses, the working hands brand is scent free.
Fitbit User
★★☆☆☆January 7, 2024
Like petroleum jelly with a strong scent
I couldn't use it. I took it to work and put it in the bathroom for people to use if they want. I was looking for petroleum jelly than a cream. I can use petroleum jelly - it's cheaper and no scent.
ivbellVerified purchase